王梅祥 教授 博士生导师

电话:010-62796761

传真:010-62796761

E-mail: wangmx@mail.tsinghua.edu.cn

 

 

教育背景

1979.9 - 1983.7,上海复旦大学化学系学习,获理学学士学位

1986.9 - 1989.7,中国科学院化学研究所硕士研究生, 获理学硕士学位

1989.7-1992.3,中国科学院化学研究所博士研究生,获理学博士学位

工作履历

1983.8-1986.8      北京有色金属研究总院工作

1992.4 – 2009.5     中国科学院化学所工作,历任助理研究员(1992.4-1993.12),副研究员(1993.12-1997.6),研究员(1997.7-2009.5)和博士生导师(1998.5-2009.5)

2009.5 –现在         清华大学化学系教授、博士生导师

学术兼职

Org. Chem. Front. (associate editor)

International Conference on Calixarene (advisory committee member)

Asian J. Org. Chem. (international advisory board member);

Beilstein J. Org. Chem. (advisory board member)

Supramol. Chem. (editorial board member)

Chinese J. Chem. (executive editorial board member)

化学学报(顾委)

有机化学(编委)

中国科学 – 化学 (编委)

国家自然科学基金会化学部专家咨询委员会委员

 

研究领域

1.  杂杯芳烃(heteracalixaromatics)和冠芳烃(corona[n]arenes)的大环化学与超分子化学

2.  阴离子-p非共价相互作用及分子识别

3.  高价有机铜化学

4.  基于叔烯酰胺合成子的有机杂环合成反应方法

5.  微生物细胞催化的腈和酰胺的对映选择性转化反应及在有机合成中的应用

 

奖励与荣誉

近期主要获奖

1.2006,礼来公司“礼来科研成就奖”(Eli Lilly & Company, Scientific Excellence Award)

2.2005,中国化学会有机化学委员会“第三届中国化学会有机合成专业委员会有机合成创造奖金奖”

3.2004,国家人事部“新世纪百千万人才工程国家级人员”

4.1999,国务院“政府特殊津贴”

5.1998,香港求是科学基金会“求是杰出青年学者奖”

6.1998,茅以升科技教育基金“茅以升北京青年科技奖”

7.1997, 国家自然科学基金会“杰出青年基金”

学术成果

部分近期代表性论文、论著和译著

1.     Zhi-Chen Wu, Qing-Hui Guo, Mei-Xiang Wang,* “Corona[5]arenes Accessed by a Macrocycle-to-Macrocycle Transfromation and a One-pot Three-Component Reaction”, Angew Chem. Int. Ed. 2017, 56, DOI: 10.1002/anie.201703008.

2.     Xin-Ming Xu, Liang Zhao, Jieping Zhu, Mei-Xiang Wang,* “Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]isoquinoline Alkaloid Derivatives”, Angew Chem. Int. Ed. 2016, 55, 3799-3803.

3.     Yun Zhang, Yu-Fei Ao, Zhi-Tang Huang, De-Xian Wang,* Mei-Xiang Wang,* Jieping Zhu,* “Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct”, Angew Chem. Int. Ed. 2016, 55, 5282-5285.

4.     Qing-Hui Guo, Liang Zhao, Mei-Xiang Wang,* “Synthesis and molecular recognition of water-soluble S6-corona[3]arene[3]pyridazines”, Angew Chem. Int. Ed. 2015, 54, 8386-8389.

5.     Mei-Xiang Wang,* “Enantioselective biotransformations of nitriles in organic synthesis”, Acc. Chem. Rev. 2015, 48, 602-611.

6.     Mei-Xiang Wang,* “Exploring tertiary enamides as versatile synthons in organic synthesis”, Chem. Commun. 2015, 51, 6039-6049 (an invited feature article).

7.     Qing-Hui, Guo, Zhan-Da Fu, Liang Zhao, Mei-Xiang Wang,* “Synthesis, structure, and properties of O6-corona[3]arene[3]tetrazines”, Angew. Chem. Int. Ed. 2014, 53, 13548-13552.

8.     Hu, Zhang, Bo Yao, Liang Zhao, De-Xian Wang, Bo-Xing Xu, Mei-Xiang Wang,* “Direct synthesis of high-valent aryl-Cu(II) and aryl-Cu(III) compounds: mechanistic insight into arene C-H bond metalation”, J. Am. Chem. Soc. 2014, 136, 6326-6332.

9.     Chuan-Hu Lei, De-Xian Wang, Liang Zhao, Jieping Zhu, Mei-Xiang Wang,* “Synthesis of substituted pyridines from cascade [1+5] cycloaddition of isonitriles to N-formylmethyl-substituted enamides, aerobic oxidative aromatization, and acyl transfer reaction”, J. Am. Chem. Soc. 2013, 135, 4708-4711.

10.  De-Xian Wang,* Mei-Xiang Wang,* “Anion-p interactions: generality, binding strength and structure”, J. Am. Chem. Soc. 2013, 135, 892-897.

11.  Mei-Xiang Wang,* “Nitrogen and oxygen bridged calixaromatics: synthesis, structure, functionalization, and molecular recognition”, Acc. Chem. Res. 2012, 45, 182-195.

12.  Cai-Yan Gao, Liang Zhao,* Mei-Xiang Wang,* “Stabilization of a reactive polynuclear silver carbide cluster through the encapsulation within a supramolecular cage”, J. Am. Chem. Soc. 2012, 134, 824-827.

13.  Shuo Tong, De-Xian Wang, Liang Zhao, Jieping Zhu, Mei-Xiang Wang*, “Enantioselective synthesis of 4-hydroxytetrahydropyridine derivatives by intramolecular addition of tertiary enamides to aldehydes”, Angew. Chem. Int. Ed. 2012, 124, 4493-4496.

14.   Placido Neri, Jonathan Sessler, Mei-Xiang Wang (Eds.) “Calixarenes and Beyond”, Springer, 2016.

15.   Jieping Zhu, Qian Wang, Mei-Xiang Wang (Eds.), “Multicomponent Reactions in Organic Synthesis”, Wiley-VCH, Weinheim, 2014.

16.  《化学生物学进展》张礼和,王梅祥(主编),化学工业出版社,2005

17.  《有机化学-结构与功能》K. Peter C. Vollhardt, Neil E. Schore原著第四版,戴立信,席振锋,王梅祥(翻译),化学工业出版社,2006

18.  《手性合成与手性药物》林国强,王梅祥(主编),杜灿屏,吴镭(副主编),化学工业出版社,2008