Prof. Zhaolong Li Ph.D

Director of Experimental Chemistry Center,

Department of Chemistry, TsinghuaUniversity, Beijing, 100084, P.R. China

Tel. 86-10-62795773

Fax: 86-10-62771149

E-mail: zhlli@mail.tsinghua.edu.cn

 

Education

Ph.D.(Jun. 1995), Orgnic Chemistry, State Key Laboratory of Applied Organic

Chemistry, LanzhouUniversity. GansuProvence, P.R.China

(July 1978), Graduate from Polymer Chemistry, LanzhouUniversity,

GansuProvence, P.R.China

 

Experience

July 1997-present Associate professor, Teaching commitments at Department of Chemistry, TsinghuaUniversity.

July 1995-June 1997 Postdoctoral research fellow. Organic Phosphorus Chemistry and Life Science, Bioorganic Phosphorus Chemistry Laboratory, TsinghuaUniversity,

Aug. 1978- July 1995 faculty of Department of Chemistry, Lanzhou University, GansuProvence, P.R.China

July 1997-present faculty of Department of Chemistry, TsinghuaUniversity, Beijing, 100084, P.R.China

May 2001- Dec. 2002 Visiting scholar of Department of Biochemistry, Oklahoma State University, Stillwater, OK. USA

  

Courses

Organic chemistry Experiment

Organic Chemistry

Advanced organic Chemistry

 

Awards

1992 The 3rd Prize of the Advancement of Science and Technology by Gansu Province of China

1993 The 2nd Prize of the Textbook by State Education Committee of China

1998 The Prize for Excellent Post-doctor of Tsinghua Univerisity

 

Research Interests

Physical Organic Chemistry; Polymer Chemistry,Free Radical Biology

Studies on the synthesis of controlling copolymer by living free radical polymerization of carbon-carbon bond iniferter with nitoxide-mediated

Free radical bio-antioxidant of polyhydroxyl anthraquinone structure, function and chemical biology action

Peptide self-formation from active amino acid or high coordinated phosphorus, synthesis method and mechanism.

synthesis of labelled pharmaceutical with fluorescence and preparation of core-shell nanoparticle of amphiphilic block copolymer for drug carrier by living free radical polymerization.

 

Selected Publications

1. Teng B, Bai YP, Chang Y, Chen SZ & Li ZL*, Technetium-99m-labeling and synthesis of thymidine analogs: Potential candidates for tumor imaging, Bioorganic & Medicinal Chemistry Letters, 2007, 17, 3440-3444

2. Bai YP, Teng B, Chen SZ, Chang Y, Li ZL*, Preparation of Magnetite Nanoparticles Coated with an Amphiphilic Block Copolymer: A Potential Drug Carrier with a Core-Shell-Corona Structure for Hydrophobic Drug Delivery, Macromolecular Rapid Communications, 2006, 27,2107-2112

3. Li ZL, Fu H, Gong HG and Zhao YF, Convenient solid-phase synthesis of oligopeptides using pentacoordinated phosphoranes with amino acid residue as building blocks Bioorganic ,Chemistry, 2004, 32(3); 178-182

4. Zhang L, Li ZL, Quian B, Yu LD and Yu CA, Nonoxidizable ubiquinol derivatives that are suitable for the study of the ubiquinol oxidation site in the cytochrome bc1 complex, Biochimic Biophysical Acta, 2002, 1556; 226-230

5. Fu H, Li ZL, Zhao YF and Tu GZ, Oligomerization of N,O-Bis(trimethylsily)-α-amino Acids into Peptides Mediated by o-Phenylene Phosphorochloridate, Journal of the America Chemical Society, 1999, 121; 291-275