An Injectable, Self-Healing Hydrogel to Repair the Central Nervous System

  Cell therapy is a rapid growing new therapeutic strategy with many advantages including good curative effects, little side effects and personalized treatments etc.. It offers a new choice (sometimes the last option) to clinical treatments of cancer, immunological and degenerative diseases.
  The repair of the central nervous system is a world-class challenge in Medicine, with the support from the Central Organization Department ‘1000 Plan’ and the National Natural Science Foundation of China, the research group of professor Yen Wei (the Department of Chemistry, Tsinghua University) developed a bio-compatible and self-healing hydrogel through facilely utilizing cheap and abundant raw materials (chitosan). Recently, they collaborated with the research group of professor Shan-hui Hsu in National Taiwan University to repair zebrafish’s impaired central nervous system using that self-healing hydrogel as the stem cell carrier. The experiment results showed excellent repair effects, indicating the key and promotion role the self-healing hydrogel during repairing the central nervous system in this cell therapy trial. The research work was published online at 7 May on Advanced Materials. (Ting-Chen Tseng et al., Article first published online: 7 MAY 2015,DOI: 10.1002/adma.201500762)