Prof. Dr. Mei-Xiang WANG

Tel: 86-10-62797527


Prof. Dr. Wang graduated from Fudan University. After spending 3 years in Beijing General Research Institute of Non-ferrous Metals as a research associate, he joined Institute of Chemistry, Chinese Academy of Sciences (ICCAS) at Beijing and obtained his master degree (1989) and PhD (1992). He then worked at ICCAS ranking from assistant professor, associate professor to professor. He has joined Tsinghua University since the May of 2009. His research interests include (1) macrocyclic and supramolecular chemistry of heteracalixaromatics, corona[n]arenes and belt[n]arenes, (2) anion-π non-covalent bond interactions, (3) high valent organocopper chemistry, (4) catalytic asymmetric reactions of tertiary enamides, and (5) enantioselective biotransformations of nitriles and amides and their applications in synthesis of natural products and bioactive compounds.

Academic memberships
Chinese Chemical Society (member)
Royal Society of Chemistry (follow)
International Conference on Calixarene (advisory committee member)
Asian J. Org. Chem. (international advisory board member)
Beilstein J. Org. Chem. (advisory board member)
Supramol. Chem. (editorial board member)

Selected recent publications
1. Tan-Hao Shi, Shuo Tong, Mei-Xiang Wang*, “Construction of hydrocarbon nanobelts”, Angew. Chem. Int. Ed. 2020, 59, DOI: 10.1002/anie.202002827.
2. Shen-Yi Guo, Qing-Hui Guo, Shuo Tong, Mei-Xiang Wang.* Synthesis of electron-deficient corona[5]arenes and their selective complexation with dihydrogen phosphate: cooperative effects of anion-π interactions. Angew. Chem. Int. Ed. 2020, 59,
3. Tan-Hao Shi, Qing-Hui Guo, Shuo Tong, Mei-Xiang Wang.* Toward the synthesis of a highly strained hydrocarbon belt. J. Am. Chem. Soc. 2020, 142, 4576-4580.
4. Qian Zhang, Yan-E Zhang, Shuo Tong, Mei-Xiang Wang.* Hydrocarbon belts with truncated cone structures. J. Am. Chem. Soc. 2020, 142, 1196-1199.
5. Qian Zhang, Ting Wang, Xinhao Zhang,* Shuo Tong, Yun-Dong Wu, Mei-Xiang Wang.* Radical reactivity, catalysis, and reaction mechanism of arylcopper(II) compounds: the missing link in organocopper chemistry. J. Am. Chem. Soc. 2019, 141, 18341-18348.
6. Han-Bin Liu, Qian Zhang, and Mei-Xiang Wang.* Synthesis, structure and anion binding property of electron deficient tetrahomocorona[4]arenes: shape selectivity in anion-π interactions. Angew. Chem. Int. Ed. 2018, 57, 6536-6540.
7. Qian Zhang, Yang Liu, Ting Wang, Xinhao Zhang,* Chao Long, Yun-Dong Wu, Mei-Xiang Wang.* Mechanistic study on Cu(II)-catalyzed oxidative cross-coupling reaction between arenes and boronic acids under aerobic conditions. J. Am. Chem. Soc. 2018, 140, 5579-5587.
8. Zhi-Chen Wu, Qing-Hui Guo, Mei-Xiang Wang.* Corona[5]arenes accessed by a macrocycle-to-macrocycle transformation route and a one-pot Three-component reaction”, Angew Chem. Int. Ed. 2017, 56, 7151-7155.
9. Xin-Ming Xu, Liang Zhao, Jieping Zhu, Mei-Xiang Wang.* Catalytic asymmetric tandem reaction of tertiary enamides: expeditious synthesis of pyrrolo[2,1-a]isoquinoline alkaloid derivatives.” Angew Chem. Int. Ed. 2016, 55, 3799-3803.
10. Qing-Hui Guo, Liang Zhao, Mei-Xiang Wang.* Synthesis and molecular recognition of water-soluble S6-corona[3]arene[3]pyridazines. Angew Chem. Int. Ed. 2015, 54, 8386-8389.

Selected reviews and edited books
11. Mei-Xiang Wang*, “Nitrogen and oxygen bridged calixaromatics: synthesis, structure, functionalization, and molecular recognition”, Acc. Chem. Res. 2012, 45, 182-195.
12. Mei-Xiang Wang.* Enantioselective biotransformations of nitriles in organic synthesis. Acc. Chem. Res. 2015, 48, 602-611.
13. Mei-Xiang Wang*, “Exploring tertiary enamides as versatile synthons in organic synthesis”, Chem. Commun. 2015, 51, 6039-6049 (an invited feature article).
14. Mei-Xiang Wang*, “Coronarenes: recent advances and perspectives on macrocyclic and supramolecular chemistry”, Sci. China Chem. 2018, 61, 993-1003.
15. Qian, Wang, De-Xian Wang, Mei-Xiang Wang*, Jieping Zhu*, “Still unconquered: enantioselective Passerini and Ugi multicomponent reactions”, Acc. Chem. Res. 2018, 51, 1290-1300.
16. Placido Neri, Jonathan L. Sessler, Mei-Xiang Wang (Eds.), “Calixarenes and Beyond”, Springer, Switzerland, 2016.
17. Jieping Zhu, Qian Wang, Mei-Xiang Wang (Eds.), “Multicomponent Reactions in Organic Synthesis”, Wiley-VCH, Weinheim, 2015.