马超，副研究员
北京市海淀区清华大学生物医学馆
Email:chaoma_chem@tsinghua.edu.cn
研究方向：
化学生物学、生物制造、绿色矿山
成果小结：
1. 挖掘极端生境资源，构建非模式细胞工厂，实现关键金属绿色开采和高值利用；
2. 在分子层面开展蛋白质理性设计，实现生物杂化材料多级组装和宏量制造。
资助与奖励：
国家自然科学基金委优秀青年科学基金
国家重点研发计划青年科学家项目
教育部联合基金青年人才项目
北京市科技新星
中关村雏鹰人才计划
绿色矿山青年科学技术奖
Bioorganic Chemistry 化学生物学新锐科学家
学术兼职：
中国生物材料学会骨修复材料与器械委员会委员
研究论文：
1. Qian Zhang, Zhenyue Yang, Sikang Wan,* Mengqi Zhu, Lingpeng Meng, Yawei Liu, Xiaogang Liu, Hongjie Zhang, Chao Ma,* Kai Liu,* Mechanically Durable Rare-Earth Biopolymer Fibers for High-Efficiency Solar-Thermal Management, Adv. Funct. Mater., 2025: e18599.
2. 崔惠敬,王帆,李敬敬,孙静,马超*,刘凯*,张洪杰,材料合成生物学研究进展及展望, 中国科学基金, 2025, 39(3):432-440.
3. Qiliang Yin, Jingjing Li, Jianhua Zhang, Jiyan Leng, Kexin Zhang, Xihui Gao, Fan Wang,* Qi Yue,* Chao Ma,* Huaping Xu, Xiaogang Liu, Hongjie Zhang, Kai Liu,* Nanoshield Architecture Harnessing Neoantigen-Targeting Peptides Enables Durable Post-surgical Glioma Immunotherapy, Nano Lett., 2025, doi/10.1021/acs.nanolett.5c03459
4. R. Xia, W. Sun,* J. Liang, S. Wang,* F. Gao, Y. Liu, L. Wang, H. Zhang, Chao Ma,* K. Liu,* Few-Shot Identification of Active Therapeutic Peptide Networking with Gradient Dynamics against Cancer, Adv. Healthcare Mater., 2025, 2501753.
5. R. Su, Chao Ma,* B. Han,* H. Zhang, K. Liu,* Proteins for Hyperelastic Materials, Small, 2025, 2406388.
6. Sikang Wan, Baiqi Shao*, Chao Ma*, Hongjie Zhang, Kai Liu*, Genetically Encoded Design and Biomanufacturing of Mechanical Protein Materials, Acc. Mater. Res., 2025, DOI: 10.1021/accountsmr.5c00169.
7. Xin Zhang, Jingjing Li, Chao Ma*, Hongjie Zhang, Kai Liu*, Biomimetic Structural Proteins: Modular Assembly and High Mechanical Performance, Acc. Chem. Res. 2023, 56, 2664-2675.
8. M. Li , B. Liu , W. Xu, L. Zhao, Z. Wang, H. He, J. Li, F. Wang, Chao Ma*, K. Liu,* H. Zhang, Engineering Protein Coacervates into a Robust Adhesive for Real-Time Skin Healing, Engineering, 2023, 31, 76-85.
9. Xiaoyuan Zhao, Xiang Li, Bo Li, Yao Sun, Yejiao Shi, Huaxing Shen, Fan Wang, Jingjing Li, Farukh Sharopov, Zainiddin Mukhiddinov, Chao Ma*, Kai Liu*, Hong-Gang Hu*, A robust protein-peptide co-assembling nanoformulation (PePCAN) platform with significant cell-entry characteristics for targeted cancer therapy, Chem. Eng. J., 2023, 543, 139886.
10. Shidong Wang, Bo Li, Hongliang Zhang, Jiayin Chen, Xin Sun, Jie Xu, Tingting Ren, Yuanyuan Zhang, Chao Ma*, Wei Guo*, Kai Liu*, Improving Bioavailaibity of Hydrophobic Prodrugs through Supramolecular Nanocarriers Based on Recombinant Proteins for Osteosarcoma Treatment. Angew. Chem. Int. Ed., 2021, 60(20), 11252-11256.
11. Chao Ma#, Jing Sun#, Bo Li#, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert Gӧstl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu,* Andreas Herrmann,* Ultra-strong bio-glue from genetically engineered polypeptides, Nat. Commun., 2021, 12, 3613.
12. Chao Ma#, Bo Li#, Jinrui Zhang#, Yao Sun, Jingjing Li, Hangcheng Zhou, Jianlei Shen, Rui Gu, Jiangchao Qian, Chunhai Fan, Hongjie Zhang, Kai Liu,* Significantly Improving the Bioefficacy for Rheumatoid Arthritis with Supramolecular Nanoformulations. Adv. Mater., 2021: e2100098.
13. Chao Ma#, Jingjin Dong#, Marco Viviani#, Isotta Tulini, Nicola Pontillo, Sourav Maity, Yu Zhou, Wouter H. Roos, Kai Liu,* Andreas Herrmann,* Giuseppe Portale,* De Novo Rational Design of a Freestanding, Supercharged Polypeptide, Proton-Conducting Membrane. Science Advances, 2020, 6(29): eabc0810.
14. Chao Ma, Anke Malessa, Arnold J. Boersma, Kai Liu, Andreas Herrmann,* Supercharged Proteins and Polypeptides. Adv. Mater., 2020: e1905309.
15. Chao Ma, Bo Li, Baiqi Shao, Baiheng Wu, Dong Chen, Juanjuan Su,* Hongjie Zhang, Kai Liu,* Anisotropic Protein Organofibers Encoded with Extraordinary Mechanical Behavior for Cellular Mechanobiology Applications. Angew. Chem. Int. Ed., 2020, 59(48): 21481-21487.
16. Chao Ma#, Juanjuan Su#, Bo Li, Andreas Herrmann, Hongjie Zhang, Kai Liu,* Solvent-Free Plasticity and Programmable Mechanical Behaviors of Engineered Proteins. Adv. Mater., 2020: e1907697.
17. Chao Ma#, Juanjuan Su#, Yao Sun#, Yang Feng, Nolan Shen, Bo Li, Yingxia Liang, Xintong Yang, Hui Wu, Hongjie Zhang, Andreas Herrmann,* Rudolph E. Tanzi, Kai Liu,* Can Zhang,* Significant Upregulation of Alzheimer's Beta-Amyloid Levels in a Living System Induced by Extracellular Elastin Polypeptides. Angew. Chem. Int. Ed., 2019, 58(51): 18703-18709.
