王歆燕 博士,副研究员

Tel:86-10-62792789

Email:wangxinyan@tsinghua.edu.cn

教育背景

2000.9-2003.12 清华大学化学系 博士

1997.9-2000.7 中南大学化学系 硕士

1992.9-1996.7 中南大学化学系 本科

工作履历

2011.3-2012.3 美国麻省理工学院化学系 访问学者(Stephen. L. Buchwald教授课题组)

2011.1- 清华大学化学系 副研究员

2006.11-2010.12 清华大学化学系 助理研究员

2004.1-2006.10 清华大学化学系 博士后

研究领域

有机合成

不对称合成

含氮杂环的合成方法学研究

学术成果

代表性论文:

1. Li H, Shan L, Liu C, Liu N, Liu C, Wang X,* Hu, Y,* Chemospecific C3- and C2-Olefinations of Isatins by TfOH-Promoted Tandem Aldol-Grob and Semiacetalization-Grob Fragmentations, Organic Letters, 2023, 25, 4656-4660.

2. Shan L, Li H, Zheng W, Wang X, Wang X,* Hu, Y,* Tandem Synthesis of 2Azaspiro[4.5]deca-1,6,9-trien-8-ones Based on Tf2OPromoted Activation of N(2-Propyn-1-yl) Amides, Journal of Organic Chemistry, 2023, 88, 525-533.

3. Shan L, Li H, Zheng W, Wang X, Wang X,* Hu, Y,* Mechanistic Insights into Tf2OPromoted Electrophilic Activation of 2Propynamides and a New Synthesis of 2,4-Disubstituted Quinolines, Organic Letters, 2022, 24, 8806-8811.

4. Shan L, Weng Y, Li H, Min L, Wang X,* Hu, Y,* Bischler−Napieralski Synthesis of Polycyclic N‑Heteroaromatics Based on Tf2O‑Promoted Electrophilic Activation of N‑Aryl-2-Propynamides, Journal of Organic Chemistry, 2022, 87, 4124-4133.

5. Shan L, Li H, Min L, Weng Y, Wang X,* Hu, Y,* Bischler−Napieralski Synthesis of 6‑Alkynyl Phenanthridines Based on Tf2O‑Promoted Electrophilic Activation of N‑Aryl-2-propynamides, Journal of Organic Chemistry, 2021, 86, 15726-15732.

6. Li H, Shan L, Min L, Weng Y, Wang X,* Hu, Y,* Tandem Synthesis of 1,3-Disubstituted Naphthalenes via TfOH Promoted Directed-Aldol and Friedel−Crafts Reactions, Journal of Organic Chemistry, 2021, 86, 15011-15019.

7. Weng Y, Min L, Zeng X, Liu C, Shan L, Wang X,* Hu, Y,* General Synthesis of α‑Alkyl Ynones from Morpholine Amides and 1‑Copper(I) Alkynes Promoted by Triflic Anhydride, Organic Letters, 2020, 22, 8296-8301.

8. Luo D, Min L, Zheng W, Shan L, Wang X,* Hu, Y,* Introduction of N,N'-disulfonylhydrazines as new sulfonylating reagents for highly efficient synthesis of (E)-β-iodovinyl arenesulfones under mild conditions, Chinese Chemical Letters, 2020, 31, 1877-1880.