马超，副研究员
北京市海淀区清华大学生物医学馆
Email:chaoma_chem@tsinghua.edu.cn
工作及教育经历：
2021- 清华大学化学系 副研究员
2019-2020 美国哈佛大学 博士后
2013-2019 荷兰格罗宁根大学 博士
2010-2013 中国药科大学 硕士
2006-2010 中国药科大学 学士
奖励与资助
国家自然科学基金委优秀青年科学基金
国家重点研发计划青年科学家项目
教育部联合基金青年人才项目
北京市科技新星
中关村雏鹰人才计划
中国稀土学会/中国稀土行业协会稀土科学技术奖
研究方向
1. 借助微生物底盘改造构建稀土细胞工厂，实现关键资源绿色开采和高值利用；
2. 通过生物合成化学技术，开展蛋白质理性设计，实现高鲁棒生物材料的组装和宏量制造；
3. 开发生物无机长效纳米技术平台，发展下一代药物递送载体。
科研成果
1. Xin Zhang, Jingjing Li, Chao Ma*, Hongjie Zhang, Kai Liu*, Biomimetic Structural Proteins: Modular Assembly and High Mechanical Performance, Acc. Chem. Res., 2023, 56, 2664–2675.
2. Huijing Cui, Xin Zhang, Jing Chen, Xining Qian, Yuewen Zhong, Chao Ma*, Hongjie Zhang, Kai Liu*, The Construction of Microbial Synthesis System for Rare Earth Enrichment and Material Applications, Adv. Mater., 2023, 35, 2303457.
3. Xiaoyuan Zhao, Xiang Li, Bo Li, Yao Sun, Yejiao Shi, Huaxing Shen, Fan Wang, Jingjing Li, Farukh Sharopov, Zainiddin Mukhiddinov, Chao Ma*, Kai Liu*, Hong-Gang Hu*, A robust protein-peptide co-assembling nanoformulation (PePCAN) platform with significant cell-entry characteristics for targeted cancer therapy, Chem. Eng. J., 2023, 543, 139886.
4. Shidong Wang, Bo Li, Hongliang Zhang, Jiayin Chen, Xin Sun, Jie Xu, Tingting Ren, Yuanyuan Zhang, Chao Ma*, Wei Guo*, Kai Liu*, Improving Bioavailaibity of Hydrophobic Prodrugs through Supramolecular Nanocarriers Based on Recombinant Proteins for Osteosarcoma Treatment. Angew. Chem. Int. Ed., 2021, 60(20), 11252-11256.
5. Chao Ma#, Jing Sun#, Bo Li#, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert Gӧstl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu*, Andreas Herrmann*, Ultra-strong bio-glue from genetically engineered polypeptides, Nat. Commun., 2021, 12, 3613.
6. Chao Ma#, Jingjin Dong#, Marco Viviani#, Isotta Tulini, Nicola Pontillo, Sourav Maity, Yu Zhou, Wouter H. Roos, Kai Liu*, Andreas Herrmann*, Giuseppe Portale*, De Novo Rational Design of a Freestanding, Supercharged Polypeptide, Proton-Conducting Membrane. Science Advances, 2020, 6(29): eabc0810.
7. Chao Ma#, Juanjuan Su#, Yao Sun#, Yang Feng, Nolan Shen, Bo Li, Yingxia Liang, Xintong Yang, Hui Wu, Hongjie Zhang, Andreas Herrmann*, Rudolph E. Tanzi, Kai Liu*, Can Zhang*, Significant Upregulation of Alzheimer's Beta-Amyloid Levels in a Living System Induced by Extracellular Elastin Polypeptides. Angew. Chem. Int. Ed., 2019, 58(51): 18703-18709.
8. Chao Ma#, Bo Li#, Jinrui Zhang#, Yao Sun, Jingjing Li, Hangcheng Zhou, Jianlei Shen, Rui Gu, Jiangchao Qian, Chunhai Fan, Hongjie Zhang, Kai Liu*, Significantly Improving the Bioefficacy for Rheumatoid Arthritis with Supramolecular Nanoformulations. Adv. Mater., 2021: e2100098.
9. Chao Ma, Anke Malessa, Arnold J. Boersma, Kai Liu, Andreas Herrmann*, Supercharged Proteins and Polypeptides. Adv. Mater., 2020: e1905309.
10. Chao Ma, Bo Li, Baiqi Shao, Baiheng Wu, Dong Chen, Juanjuan Su*, Hongjie Zhang, Kai Liu*, Anisotropic Protein Organofibers Encoded with Extraordinary Mechanical Behavior for Cellular Mechanobiology Applications. Angew. Chem. Int. Ed., 2020, 59(48): 21481-21487.
11. Chao Ma#, Juanjuan Su#, Bo Li, Andreas Herrmann, Hongjie Zhang, Kai Liu*, Solvent-Free Plasticity and Programmable Mechanical Behaviors of Engineered Proteins. Adv. Mater., 2020: e1907697.
12. Jing Sun#, Chao Ma#, Sourav Maity#, Fan Wang, Yu Zhou, Giuseppe Portale, Robert Gostl, Wouter H. Roos, Hongjie Zhang, Kai Liu*, Andreas Herrmann*, Reversibly Photo-Modulating Mechanical Stiffness and Toughness of Bioengineered Protein Fibers. Angew. Chem. Int. Ed., 2021, 60(6): 3222-3228.
13. Lei Zhang#, Chao Ma#, Jing Sun, Baiqi Shao, Giuseppe Portale, Dong Chen, Kai Liu*, Andreas Herrmann*, Genetically Engineered Supercharged Polypeptide Fluids: Fast and Persistent Self-Ordering Induced by Touch. Angew. Chem. Int. Ed., 2018, 57(23): 6878-6882.
14. Huige Yang#, Chao Ma#, Kaiyong Li, Kai Liu, Mark Loznik, Rosalie Teeuwen, Jan C. M. Van Hest, Xin Zhou*, Andreas Herrmann*, Jianjun Wang*, Tuning Ice Nucleation with Supercharged Polypeptides. Adv. Mater., 2016, 28(25): 5008-5012.
