刘强 教授、化学系副系主任
电话：010-6279 6906
E-mail：qiang_liu@mail.tsinghua.edu.cn
课题组主页: http://cbms.chem.tsinghua.edu.cn/liugroup
通讯地址：清华大学化学系国强楼203室
教育背景
2003.9-2007.7 武汉大学化学与分子科学学院，获理学学士学位
2007.8-2012.8 武汉大学化学与分子科学学院，获理学博士学位 （导师: 雷爱文教授）
工作履历
2012.9-2015.5 德国莱布尼兹催化研究所 博士后（导师: Matthias Beller教授）
2015.6-2025.6 清华大学化学系 副教授
2025.7- 清华大学化学系 教授
研究领域
金属氢配位化学与催化
奖励与荣誉
1. 德国洪堡奖学金 （2012年）
2. Thieme Chemistry Journals Award（2017年）
3. 国家自然科学基金委优秀青年基金（2018年）
4. 清华大学教学优秀奖（2021年）
5. 国家自然科学基金委员会“杰出青年科学基金”（2022年）
6. Asian Core Program Lectureship Award （2023）
7. 清华大学优秀博士论文指导教师（2022, 2024）
8. 霍英东教育基金会高等院校青年科技奖二等奖（2024）
9.德国洪堡基金会Friedrich Wilhelm Bessel Research Award（2025）
10. 北京市科学技术奖杰出青年奖（2025）
承担项目
1. 国家自然科学基金委员会优秀青年科学基金（2018）
2. 国家自然科学基金委员会杰出青年科学基金（2022）
3. 清华大学笃实拔尖专项（2025）
4. 国家自然科学基金委员会原创探索计划项目（2025）
学术成果
代表性论文：
[1] J. Yang, H. Li, Q. Wang*, Q. Liu*, Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling, Nat. Synth. 2026, 10.1038/s44160-025-00947-9.
[2] X. Rong, Y. Ren, Y. Chen, C. Li, J. Wang, Z. Chen, L. Tao, Z*. Wei*, S. Ma*, Q. Liu*, Tunable cobalt-catalysed hydrogenation of allenes enabled by multiple metal–ligand cooperative functionalities, Nat. Chem. 2025, 17, 1469-1479.
[3] H. Li, M. Fan, Q. Liu*, Dinuclear Magnesium-Catalyzed Hydroboration: Unveiling Metal–Ligand Cooperative Activation of Polar Unsaturated Bonds, J. Am. Chem. Soc. 2025, 147, 37708-37718.
[4] H. Yang, S. Liu, H. Dong, H. Huang, Y. Wang*, W. Hao*, Y. Lan*, Q. Liu*, Amplifying the Reactivity of Anionic Mn(I)–H Catalysts via the Cation Effect: Mechanistic Investigation and Application to the Hydrogenation of α-Trisubstituted Carboxylic Esters, J. Am. Chem. Soc. 2025, 147, 13491-13501.
[5] B. Liu, Q. Lu, X. X. Hu, D. Li, Z. Xu, Lu*, Y Fu*, Q. Liu*, Regiodivergent Hydroamidation of Alkenes via Cobalt-Hydride Catalysis, J. Am. Chem. Soc. 2025, 147, 13983-13992.
[6] H. Yang, H. Huang, Y. Wang, S. Long, Q. Liu*, Ligand-Controlled Stereodivergent Manganese-Catalyzed Hydroalkoxylation of Alkynylnitriles to Access (E)- and (Z)-3-Alkoxyvinylnitriles, Angew. Chem. Int. Ed. 2025, 64, e202511311.
[7] M. Wang, S. Liu, H. Liu, Y. Wang, Y. Lan*, Q. Liu* Asymmetric hydrogenation of ketimines with minimally different alkyl groups, Nature 2024, 631, 556-562.
[8] S. Liu, H. Yang, Y. wang, Q. Zhao, Y. Wang*, Q. Liu*, Y. Lan* Enhancing Hydride Transfer in Catalytic Hydrogenation via σ-Electron-Induced Polarization of Imines, J. Am. Chem. Soc. 2024, 146, 16357-16362.
[9] Z. Li, B. Liu, C. Y. Yao, G. W. Gao, J. Y. Zhang, Y. Z. Tong, J. X. Zhou, H. K. Sun, Q. Liu*, X. Lu*, Y. Fu*, Ligand-Controlled Cobalt-Catalyzed Regio-, Enantio-, and Diastereoselective Oxyheterocyclic Alkene Hydroalkylation, J. Am. Chem. Soc. 2024, 146, 3405-3415.
[10] H. Li, M. Fan, Q. Liu*, Unveiling the Unique Reactivity of Anionic Mn(I) Complexes via Metal–Ligand Cooperation: Nucleophilic Attack on C(sp3)–X Bonds, J. Am. Chem. Soc. 2024, 146, 26649-26656.
[11] Y. Wang, H. Li, H. Yang, M. Fan, Q. Liu*, Manganese-Catalyzed Regioselective Hydroboration of Quinolines via Metal–Ligand Cooperation, CCS Chem. 2024, 6, 1535-1546.
[12] C. Liu, X. Liu, Q. Liu* Stereodivergent asymmetric hydrogenation of quinoxalines, Chem. 2023, 9, 2585-2600.
[13] Z Wei, H Li, Y Wang, Q. Liu* A Tailored Versatile and Efficient NHC-Based NNC-Pincer Manganese Catalyst for Hydrogenation of Polar Unsaturated Compounds, Angew. Chem. Int. Ed. 2023, e202301042.
[14] B. Liu, D. Liu, X. Rong, X. Lu*, Y Fu*, Q. Liu* Ligand-Controlled Stereoselective Synthesis of 2-Deoxy-β-C-glycosides by Cobalt Catalysis, Angew. Chem. Int. Ed, 2023, e202218544.
[15] X. L. Rong, J. Yang, S. H. Liu, Y. Lan*, Q. Liu*, Remote Stereocontrol of All-Carbon Quaternary Centers via Cobalt-Catalyzed Asymmetric Olefin Isomerization, CCS Chem. 2023, 5, 1293-1300.
[16] Y. Wang, S. Liu, H. Yang, H. Li, Y. Lan*, Q. Liu*, Structure, Reactivity and Catalytic Properties of Manganese-hydride Amidate Complexes, Nat. Chem. 2022, 14, 1233-1241.
[17] C. Liu, M. Wang, Y. Xu, Y. Li, Q. Liu*, Manganese-Catalyzed Asymmetric Hydrogenation of 3H-Indoles, Angew. Chem. Int. Ed. 2022, 61, anie.202202814.
[18] X. Liu, X. Rong, S. Liu, Y. Lan and Q. Liu*, Cobalt-Catalyzed Desymmetric Isomerization of Exocyclic Olefins, J. Am. Chem. Soc. 2021, 143, 20633-20639.
[19] Y. Wang, M. Wang, Y. Li, Q. Liu*, Homogeneous Manganese-catalyzed Hydrogenation and Dehydrogenation Reactions, Chem. 2021, 7, 1180-1223.
[20] C. Liu, M. Wang, S. Liu, Y. Wang, Y. Peng, Y. Lan*, Q. Liu*, Manganese-Catalyzed Asymmetric Hydrogenation of Quinolines Enabled by π–π Interaction, Angew. Chem. Int. Ed. 2021, 60, 5108-5113.
[21] X. Liu, B. Liu, Q. Liu*, Migratory Hydrogenation of Terminal Alkynes via Tandem Base/Cobalt Relay Catalysis, Angew. Chem. Int. Ed. 2020, 59, 6750-6755.
[22] Z. Shao, Y. Li, C. Liu, W. Ai, S. Luo, Q. Liu*, Reversible Interconversion between Methanol-Diamine and Diamide for Hydrogen Storage Based on Manganese Catalyzed (de)Hydrogenation, Nat. Commun. 2020, 11, 591.
[23] Y. Wang, L, Zhu, Z. Shao, Y. Lan*, Q. Liu*, Unmasking the Ligand Effect in Manganese-Catalyzed Hydrogenation: Mechanistic Insight and Catalytic Application, J. Am. Chem. Soc. 2019, 141, 17337-17349.
[24] R. Zhong, Z. Wei, W. Zhang, S. Liu, Q. Liu*, A Practical and Stereoselective In-Situ NHC-Cobalt Catalytic System for Hydrogenation of Ketones and Aldehydes, Chem. 2019, 5, 1552-1566.
[25] W. Ai, R. Zhong, X. Liu, Q. Liu*, Hydride Transfer Reactions Catalyzed by Cobalt Complexes, Chem. Rev. 2019, 119, 2876-2953.
[26] Y. Wang, Z. Shao, K. Zhang, Q. Liu*, Manganese-Catalyzed Dual-Deoxygenative Coupling of Primary Alcohols with 2-Arylethanols, Angew. Chem. Int. Ed. 2018, 57, 15143-15147.
[27] X. Liu, W. Zhang, Y. Wang, Z-X. Zhang, Lei Jiao*, Q. Liu*, Cobalt-Catalyzed Regioselective Olefin Isomerization Under Kinetic Control., J. Am. Chem. Soc. 2018, 140, 6873-6882.
[28] S. Fu, Z. Shao, Y. Wang, Q. Liu*, Manganese-Catalyzed Upgrading of Ethanol into 1-Butanol, J. Am. Chem. Soc. 2017, 139, 11941-11948.
[29] Z. Shao, S. Fu, M. Wei, S. Zhou*, Q. Liu*, Mild and Selective Cobalt-Catalyzed Chemodivergent Transfer Hydrogenation of Nitriles, Angew. Chem. Int. Ed. 2016, 55, 14653-14657.
[30] S. Fu, N. Chen, X. Liu, Z. Shao, S. Luo*, Q. Liu*, Ligand-Controlled Cobalt-Catalyzed Transfer Hydrogenation of Alkynes: Stereodivergent Synthesis of Z- and E-Alkenes, J. Am. Chem. Soc. 2016, 138, 8588-8594.
