华瑞茂 博士、教授
联系方式：清华大学化学系 北京 100084
Tel.: +86-10-62792596; Fax: +86-10-62771149
E-mail:ruimao@mail.tsinghua.edu.cn
教育背景
1992-1996 Ph. D. 东京工业大学 (日本)
1986-1989 M. Sc. 中国科学院大连化学物理研究所
1982-1986 B. Sc. 福建师范大学化学系
工作履历
1989-1992 中国科学院大连化学物理研究所 助理研究员
1996-2002 物质工学工业技术研究所(日本) 研究员
2002-现在 清华大学化学系 教授
学术兼职
目前是国际学术杂志国际学术期刊Molecules、Sci.、Mini-Reviews in Organic Chemistry编委；国内学术期刊《液晶与显示》、《精细化工》编委；中国化学会催化学会均相催化专业委员会委员 (2011-)。曾经是国际学术杂志Catalysis Communications编委、中国区副编辑 (2005-2012)。
研究领域
炔烃化学、有机材料化学
学术成果
研究团队主要从事：(1) 基于炔烃为原料的原子经济性或高原子利用率有机合成方法学研究；(2) 液晶、OLED、OPV等有机材料分子的设计、合成及其应用研究。建立了一系列高效、高选择性构建具有生物活性、特殊光电性质的官能团化有机分子骨架的新反应和新方法。发表学术论文120多篇、授权国内外发明专利140余项；2016年获河北省科技进步一等奖 (第一完成人)、2018年获中国专利优秀奖。
部分论文
1. Jiaying Lv, Huixin Liu, Le Lu, and Ruimao Hua*
Copper(I)-Catalyzed Syntheses of Benzo[b]fluorenes by the Cascade Reactions of 2‑Alkynylbenzaldehyde N‑Tosylhydrazones and Aromatic Terminal Alkynes.
The Journal of Organic Chemistry 2022, 87, 16011-16018
2. Le Lu, Ruimao Hua*
A Monomer-Polymer-Monomer (MPM) Organic Synthesis Strategy: Synthesis and Application of Polybenzofuran for Functionalizing Benzene Ring of Benzofuran.
Asian Journal of Organic Chemistry 2021, 10, 1846-1846
3. Yiming Zhou, Ruimao Hua*
Synthesis of 1-Benzyl-, 1-Alkoxyl-, and 1-Aminoisoquinolines via Rhodium(III)- Catalyzed Aryl C−H Activation and Alkyne Annulation.
The Journal of Organic Chemistry 2021, 86, 8862-8872
4. Liyao Zheng, Ruimao Hua*
C–H Activation and Alkyne Annulation via Automatic or Intrinsic Directing Groups: Towards High Step Economy
Chemical Record 2018, 18, 556-569 (personal account).
5. Le Lu, Huixin Liu, Ruimao Hua*
HNO3/HFIP: A Nitrating System for Arenes with Direct Observation of π‑Complex Intermediates.
Organic Letters 2018, 20, 3197-3201.
6. Liyao Zheng, Yunhui Bin, Yunpeng Wang, Ruimao Hua*
Synthesis of Natural Product-like Polyheterocycles via One-Pot Cascade Oximation, C-H Activation and Alkyne Annulation.
The Journal of Organic Chemistry2016,81, 8911-8919
7. Biao Guo, Liyao Zheng, Lei Zhang, Ruimao Hua*
Synthesis of Benzofulvene Derivatives from Diarylacetylenes via Pd(II)-Catalyzed Alkyne-Directed C(sp2)-H Bond Activation.
The Journal of Organic Chemistry2015,80, 8430-8434
8. Biao Guo, Yiming Zhou, Lei Zhang, Ruimao Hua*
Bronsted Acid-Promoted One-Pot Synthesis of Chrysene Derivatives via Isochromenylium Intermediate Formedin Situ.
The Journal of Organic Chemistry2015,80, 7635-7641
9. Lei Zhang, Liyao Zheng, Biao Guo, Ruimao Hua*
One-Pot Synthesis of Multisubstituted 2-Aminoquinolines from Annulation of 1-Aryl Tetrazoles with Internal Alkynes via Double C-H Activation and Denitrogenation.
The Journal of Organic Chemistry2014,79, 11541-11548
10. Biao Guo, Liyao Zheng, Lichen Yang, Ruimao Hua*
Synthesis of Chrysene Derivatives via Copper-Catalyzed One-Pot Dimerization of 2-Alkynyl-1-acetylbenzenes.
The Journal of Organic Chemistry2014,79, 4352-4357
11. Liyao Zheng, Ruimao Hua*
Modular Assembly of Ring-Fused and π-Extended Phenanthroimidazoles via C-H Activation and Alkyne Annulation.
The Journal of Organic Chemistry 2014, 79, 3930-3936
12. Liyao Zheng, Jia Ju, Yunhui Bin, Ruimao Hua*
Synthesis of Isoquinolines and Heterocycle-Fused Pyridines via Three-Component Cascade Reaction of Aryl Ketones, Hydroxylamine, and Alkynes.
The Journal of Organic Chemistry 2012, 77, 5794-5800
13. Jie Li, Ruimao Hua*, Tao Liu
Highly Chemo- and Stereoselective Palladium-Catalyzed Transfer Semihydrogenation of Internal Alkynes Affording cis-Alkenes.
The Journal of Organic Chemistry 2010, 75, 2966-2970
14. Ming Li, Ruimao Hua*
Ru3(CO)12-Catalyzed Reactions of Catechols with Alkynes: An Atom-Economic Process for the Synthesis of 2,2-Disubstituted 1,3-Benzodioxoles from the Double Addition of the O-H Bond Across a Triple Bond.
The Journal of Organic Chemistry 2008, 73, 8658-8660
15. Hanxiang Zeng, Ruimao Hua*
Palladium-Catalyzed Hydrophenylation of Alkyne with Sodium Tetraphenylborate under Mild Conditions.
The Journal of Organic Chemistry 2008, 73, 558-562
学术论文章节编著
(1) 著者：2022年出版(Wiley-VCH GmbH)专著 “Addition Reactions with Unsaturated Hydrocarbons” 一本
(2) 著者：“Recent Advances in Organocatalysis”一书 (2016年InTech出版社出版；主编：Iyad Karame & Hassan Srour)第5章：“Organocatalytic Transformation of Carbon Dioxide”
(3) 著者：“Copper-Mediated Cross-Coupling Reactions”一书 (2013年Wiley出版社出版；主编：Gwilherm Evano & Nicolas Blanchard)第12章：“Copper-Catalyzed Alkynylation and Alkenylation Reaction of Alkynyl Derivatives: New Access to Diynes and Enynes”
(4) 客座编辑：Current Organic Chemistry, 2011年第15卷第5期特刊: Recent Progress in the Synthesis and Applications of Cyclic Compounds
(5) 著者：2008年化学工业出版社出版的《现代有机反应》丛书，第五卷“金属催化反应”中的“Sonogashira Reaction”和“Ullmann Reaction”两章。
