巨 勇（教授，博士）
工作地点和联系方式：
清华大学生命科学楼 329, 341室
北京100084，清华大学化学系
电话：（10）62792795
传真：（10）62781695
电子邮箱：juyong@tsinghua.edu.cn
主讲课程：
本科生：有机化学，有机合成设计，天然产物化学。
研究生：立体有机化学，天然有机化学。
教育背景
1982，1987，1992 兰州大学化学系理学学士，理学硕士，理学博士
工作履历
1982-1993 兰州大学化学系，助教，讲师。
1993-1995 清华大学化学系，博士后。
1995- 至今 清华大学化学系，副教授（1995 - 2003），教授（2003 - ，博士生导师）。
1996-1998 美国New Jersey州立 Rutgers大学植物系，访问学者。
2001-2002 美国Ohio州立大学化学系，高级访问学者。
2005-2006 美国South Carolina大学化学与生物化学系，访问教授。
研究领域
研究方向：
天然产物化学，有机合成化学，化学生物学。
研究领域：
生物活性天然产物的结构改造及其构效关系；
生物缀合物的化学合成及其生物学功能；
天然产物骨架功能分子的化学合成和性能。
研究概况
研究成果：
● 作为课题负责人和主要工作者，先后参加承担完成国家自然科学基金重大项目，重点项目和科技部“973”项目各1项，主持完成国家自然科学基金项目10项。
● 主编《有机合成化学与路线设计》（2002），（第2版，2007），清华大学出版社，2008年被评为北京市高等教育精品教材；2010年被评为《首届中国大学出版社图书奖》优秀教材一等奖；2012年被评为清华大学优秀教材一等奖。
● 合编《现代有机合成试剂》（2006），化学工业出版社。《现代有机合成试剂》（第2卷，2011），化学工业出版社。 参与编写《现代有机合成反应》（第3卷，2008），413-460, 化学工业出版社。《现代有机合成反应》，（第8卷，2013），199-235, 化学工业出版社。《磷与生命化学》（第8章，2005），清华大学出版社。
● 在国内外重要学术刊物上发表研究论文180余篇，申请中国专利2项。
学术成果
近期发表主要研究论文目录：
1. Hao J, Gao YX, Li Y, Yan Q, Hu J,Ju Y(巨勇).Thermosensitive triterpenoid-appended polymers with broad temperature tunability regulated by host–guest chemistry.Chem. Asian J.,2017,12,2231.
2. Li JZ, Wu JD, Cui FC, Zhao X, Li YQ, Lin Y, Li Y, Hu J,Ju Y(巨勇).A dual functional fluorescent sensor for human serum albumin andchitosan,Sensors and Actuators B,2017,243,831.
3. Wu JD, Lu JR, Liu JG, Zheng CH, Gao YX, Hu J,Ju Y(巨勇). A deoxycholic acid-based macrocycle: Recognition of mercury ion and cascade enantioselective sensing toward amino acids.Sensors and Actuators B,2017,241, 931.
4. Gao YX, Hao J, Wu JD, Li Y, Lin Y, Hu J,Ju Y(巨勇). Cooperative supramolecular helical assembly of a pyridinium-tailored methyl glycyrrhetate.Soft Matter,2016,12,8979.
5. Gao YX, Hao J, Wu JD, Zhang X, Hu J,Ju Y(巨勇). Solvent-directed assembly of a pyridinium-tailored methyl oleanolate amphiphile: stepwise growth of microrods and nanofibers.Langmuir,2016, 32, 1685.
6. Li Y, Li JZ, Zhao X, Yan Q, Gao YX, Hao J, Hu J,Ju Y(巨勇). Triterpenoid-based self-healing supramolecular polymer hydrogels formed by host–guest interactions.Chem. Eur. J.,2016,22,18435.
7. Gao YX, Hao J, Wu JD, Zhang X, Hu J,Ju Y(巨勇). Supramolecular helical nanofibers assembled from a pyridiniumfunctionalized methyl glycyrrhetate amphiphile.Nanoscale,2015,7,13568.
8. Wu JD, Zhao X,Gao YX, Hu J,Ju Y(巨勇). A steroid-salen conjugate for zinc ion recognition and its applications in test-strips, living cells imaging, and cascade recognition for dihydrogen phosphate.Sensors and Actuators B,2015,221,334.
9. Zhang M, Yin XP, Tian T, Liang Y, Li WN, Lan Y, Li J, Zhou MM,Ju Y(巨勇), Li GT. AIE- induced fluorescent vesicles containing amphiphilic binding pockets and the FRET triggered by host-guest chemistry.Chem. Commun., 2015,51,10210.
10. Zhang X, Gao YX, Lin Y, Hu J,Ju Y(巨勇). Photo-induced conversion from supramolecular to covalently linked polymers based on anthracene appended amphiphiles.Polym. Chem.,2015,6,4162.
11. Wu JD, Lu JR, Gao Y, Hu J,Ju Y(巨勇). A steroid-cumarin conjugate for cascade recognition of copper ion and dihydrogen phosphate: microstructural features and IMPLICATION logic gate properties.Sensors and Actuators B,2015,206,516.
12. Gao YX, Lu JR, Wu JD, Hu J,Ju Y(巨勇).Water tuned nano/micro-structures in redox-responsive supramolecular gel,RSC Adv.,2014,4, 63539.
13. Li WN, Tian T, Lan Y, Zhu W, Li J, Zhang M,Ju Y(巨勇),Li GT. Self-assembled main-chain poly(bile acid)s membranes that wrinkle,Polym. Chem.,2014,5, 743.
14. Lu JR, Wu JD,Ju Y(巨勇).Tuning aggregation mode induced different chirality in organogels of mono- and bis-triterpenoid derivatives and preparation of gold nanoparticles as a template,New J. Chem., 2014,38, 6050.
15. Lu JR, Chulong Liu，Hu J,Ju Y(巨勇).Synthesis and micellar mimic properties of bile acid trimmers,Bioorg. Med. Chem. Lett.,2013,23,1302.
16. Li WN, Tian T, Zhu W, Cui JC,Ju Y(巨勇),Li GT. Metal-free click approach for facilely producing main chain poly(bile acid)s,Polym. Chem.,2013,4, 3057.
17. Li WN, Xu Q, Li Y, Zhu W, Cui JC,Ju Y(巨勇),Li GT.Bile acid-based cyclic dimers exhibit fluoride coordination by cooperative aliphatic and triazole C-H segments,Tetrahedron Lett.，2013,54,3868.
18. Hu J, Wu JD, Wang Q,Ju Y(巨勇). Charge-transfer interaction mediated organogels from 18β-glycyrrhetinic acid appended pyrene,Beilstein J. Org. Chem.,2013,9,2877.
19. Lu JR,Hu J, Liu CL, Gao HX,JuY(巨勇).Water-induced gel formation of oleanlic acid-adenine conjugate and the effects of uracil derivative on the gel stability,Soft Matter,2012,8, 9576.
20. Kang X,Hu J, Gao ZB,Ju Y(巨勇), Xu CL. Synthesis, anti-proliferative and proapoptotic activity of novel oleanolic acid azaheterocyclic derivatives,MedChemComm.,2012,3,1245.
21. Hu J, Adogla EA,Ju Y(巨勇), Fan DP, Wang Q. Copper-CatalyzedOrtho-Acylation of Phenols with Aryl Aldehydes and Its Application in One-Step Preparation of Xanthones,Chem. Commun.,2012,48, 11256.
22. Hu J, Wu JD, Lu JR,Ju Y(巨勇).A Novel Dual-Responsive Macrocycle based on Glycyrrhetinic Acid,Tetrahedron Lett.,2012,53,6705.
23. Lu JR, Hu J, Song Y,Ju Y(巨勇).A new dual-responsive organogel based on uracil-appended glycyrrhetinic acid,Org. Lett.,2011,13, 3372.
24. LiWN, Li, XS, Zhu W, Lin CX,Xu D,Ju Y(巨勇),Li GT, Topochemical approach to efficiently produce main-chain poly(bile acid)s with high molecular weights,Chem. Commun.,2011,47, 7728.
25. Hu J, Lu JR, Li RF,Ju Y(巨勇).Synthesis and self-assembly properties of a glycyrrhetinic acid conjugate containing uracil and 2,6-diaminopyridine units,Soft Matter,2011,7, 891.
26. Hu J, Lu JR,Ju Y(巨勇).Steroid/Triterpenoid functional molecules based on “Click chemistry”,Chem. Asian J.,2011,6, 2636.
27. Hu J, Li RF, Lu JR,Ju Y(巨勇).Synthesis and anion recognition of a novel cyclic dimer based on oleanolic acid,Tetrahedron Lett.,2011,52, 4211.
28. Song Y, Yang RC, Ding HX, Sun Q, Xiao Q,Ju Y(巨勇).An efficient approach for the synthesis of 1′-O-a-methyl-pyrrolo[2,3-d]pyrimidine isonucleosides, Synthesis,2011, (8), 1213.
29. Song Y. Ding HX, Dou YH, Yang RC, Sun Q. Xiao Q,Ju Y(巨勇).Efficient and practical synthesis of 5′-deoxytubercidin and its analoguesviaVorbrüggen glycosylation,Synthesis,2011, (9), 1442.
