Aijun TONG
Professor Aijun TONG
Contact:
Department of Chemistry, Tsinghua University, Beijing 100084, China
Office: Rm. D317 School of Sciences Building
Tel: 86-10-62787682
E-mail: tongaj@mail.tsinghua.edu.cn
Biography:
Prof. Aijun Tong got her B.S. (1983) in Chemistry from Xinjiang University, China, M.S. (1989) and Ph.D (1992) in Analytical Chemistry from Meisei University, Tokyo, Japan. She joined the Department of Chemistry, Tsinghua University as a Lecturer from 1992, and then promoted to Associate Professor (1996) and Professor (2003). Her current research directions include the development of novel fluorescence analytical methods for bioimaging, diagnosis and therapy of diseases, as well as their mechanisms in single cell level. Her work has resulted in over 100 peer-reviewed publications and book chapters.
Research Area:
Fluorescent probes, sensors, and functional materials for bioimaging and detection
Teaching
Analytical Chemistry
Instrumental Analysis B
Advanced Analytical Chemistry (highly sensitive detection methods)
Selected Publications:
1. Yiwen Ding, Chu Zhang, Min Zhou, Yu Xiang, Aijun Tong*, Hetero-Diels-Alder Cycloaddition Reaction of Vinyl Ethers Enables Selective Fluorescent Labeling of Plasmalogens in Human Plasma Lipids, J. Org. Chem., 2023, 88(19), 13741-13748.
2. Chu Zhang, Yiwen Ding, Min Zhou, Yu Xiang, Aijun Tong*, An in Situ, Reversible Fluorescent Paper Sensor for Selective Detection of Ambient CO2, J. Mater. Chem.C, 2023, 11(1), 299-306.
3. Chu Zhang, Zicong Liang, Aijun Tong*, Fluorescent Sensing and Bio-imaging Based on Small Organic Molecular Aggregates, Sci. Sin. Chim., 2023, 53(8), 1290-1305.
4. Yue Zheng, Aijun Tong, Chapter 3, Typical AIEgens Design: Salicylaldehyde Schiff Base, Handbook of Aggregation-Induced Emission, Edited by Youhong Tang, Ben Zhong Tang, John Wiley & Sons Ltd., 2022, Volume 2, 53-96.
5. Yue Zheng, Yiwen Ding, Xiaokun Zheng, Yanli Zhang, Yu Xiang, Aijun Tong*, Long-Term Dynamic Imaging of Cellular Processes Using an AIE Lipid Order Probe in the Dual-Color Mode, Anal. Chem., 2021, 93(29), 10272-10281. (Cover page, https://pubs.acs.org/toc/ancham/93/29?ref=pdf)
6.Xiaokun Zheng, Wenbo Wu, Yue Zheng, Yiwen Ding, Yu Xiang, Bin Liu*, Aijun Tong*, Organic Nanoparticles with Persistent Luminescence for In Vivo Afterglow Imaging-Guided Photodynamic Therapy, Chem. Eur. J., 2021, 27(23), 6911-6916. (Cover page, https://chemistry-europe.onlinelibrary.wiley.com/toc/15213765/2021/27/23)
7.Jingyi Wang, Jiachen Shang, Yu Xiang, Aijun Tong*, General Method for Post-Synthetic Modification of Oligonucleotides Based on Oxidative Amination of 4‑Thio-2′-deoxyuridine, Bioconjugate Chem., 2021, 32(4), 721-728. (Cover page, https://pubs.acs.org/toc/bcches/32/4)
8.Yue Zheng, Yiwen Ding, Jiajun Ren, Yu Xiang, Zhigang Shuai*, Aijun Tong*, Simultaneously and Selectively Imaging a Cytoplasm Membrane and Mitochondria Using a Dual-Colored Aggregation-Induced Emission Probe, Anal. Chem., 2020, 92(21), 14494-14500. (Cover page, https://pubs.acs.org/toc/ancham/92/21)
9.Lu Peng, Ruirui Wei, Yifei Guo, Xiaokun Zheng, Yue Zheng, Yiwen Ding, Yu Xiang, Aijun Tong*, Tuning Emission Wavelength of Polymorphous Crystal via Controllable Alky Chain Stacking and Its Vapor- and Thermo- Responsive Fluorescence, Chem. Eur. J., 2019, 25(34), 8043-8052. (Cover page, https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.201901744)
10.Lu Peng, Shidang Xu, Xiaokun Zheng, Xiamin Cheng, Ruoyu Zhang, Jie Liu, Bin Liu*, Aijun Tong*, Rational Design of a Red-Emissive Fluorophore with AIE and ESIPT Characteristics and Its Application in Light-up Sensing of Esterase, Anal. Chem., 2017, 89(5), 3162-3168.
11.Xiaokun Zheng, Yue Zheng, Lu Peng, Yu Xiang, Aijun Tong*, Mechanoresponsive fluorescence of 2-aminobenzophenone derivatives based on amorphous phase to crystalline transformation with high “off-on” contrast ratio, J. Phys. Chem. C, 2017, 121(39), 21610-21615.
12.Yue Zheng, Xiaokun Zheng, Lu Peng, Yu Xiang, Aijun Tong*, Photoactivatable Aggregation-Induced Emission of Triphenylmethanol, Chem. Comm., 2017, 53(81), 11130-11133.
13.Kai Li, Yu Xiang, Xiaoyan Wang, Ji Li, Rongrong Hu, Aijun Tong*, Ben Zhong Tang*, Reversible Photochromic System Based on Rhodamine B Salicylaldehyde Hydrazone Metal Complex, J. Am. Chem. Soc., 2014, 136(4), 1643-1649.
14.Yu Xiang, Aijun Tong*, Yi Lu*, Abasic site-containing DNAzyme and aptamer for label-free fluorescent detection of Pb2+ and adenosine with high sensitivity, selectivity, and tunable dynamic range, J. Am. Chem. Soc., 2009, 131(42), 15352-15357.
15.Weixin Tang, Yu Xiang*, Aijun Tong*, Salicylaldehyde azines as fluorophores of induced emission enhancement characteristics, J. Org. Chem., 2009, 74(5), 2163-2166.
