Prof. Dr. Liang Zhao
Email: zhaolchem@mail.tsinghua.edu.cn
Group webpage: http://zhaogroup.chem.tsinghua.edu.cn/
Mailing Address: Room 304, Hetian Building
Department of Chemistry
Tsinghua University
Beijing 100084
P. R. China
Biography:
Dr. Liang Zhao firstly studied chemistry at the College of Chemistry and Molecular Engineering in Peking University and obtained his bachelor degree in 2002. After staying for another year as a research assistant at the State Key Laboratory for Structural Chemistry of Unstable and Stable Species also in Peking University, he enrolled in the Chemistry Department of the Chinese University of Hong Kong under the guidance of Prof. Thomas C. W. Mak and graduated with a PhD degree in Chemistry in 2007. Subsequently, he joined Prof. Peter J. Stang’s research group at University of Utah and completed two-year postdoctoral studies until September 2009. In November 2009, he joined the faculty of Chemistry Department in Tsinghua University and serves as a full professor since 2022.
Research Interests:
Organometallic Cluster Chemistry & Supramolecular Chemistry
Selected Publications:
1. Kui Xiao, Da-Yong Hou, Ni-Yuan Zhang, Wan Wang, Ming-Yi Leung, Wing-Kei Kwok, Ziyong Chen, Cong Jin, Wanhai Xu, Hao Wang, Vivian Wing-Wah Yam, Liang Zhao, “Synergistic Enhancement of Ferroptosis via Mitochondrial Accumulation and Photodynamic-Controlled Release of an Organogold(I) Cluster Prodrug”, J. Am. Chem. Soc. 2025, 147, 4482-4492.
2. Xiao-Yi Zhai, Liang Zhao, “Aurophilic interaction-based aggregation of gem-digold(I) aryls towards high spin-orbitcoupling and strong phosphorescence”, Nat. Commun. 2025, 16, 405.
3. Qian Liu, Xiao-Yi Zhai, Rui-Jun Jian, Liang Zhao, “Divergent Catalytic Behaviors of Assembled Organogold(I) Clusters Derived from Enyne Cyclization”, Chem. Sci. 2024, 15, 11311–11320.
4. Jian Tang, Siqi Zhang, Bo-Wei Zhou, Wan Wang, Liang Zhao, “Hyperconjugative Aromaticity-Based Circularly Polarized Luminescence Enhancement in Polyaurated Heterocycles”, J. Am. Chem. Soc. 2023, 145, 23442–23451.
5. Siqi Zhang, Liang Zhao, “Anaerobic photoinduced Cu(0/I)-mediated Glaser coupling in a radical pathway”, Nat. Commun. 2023, 14, 6741.
6. Siqi Zhang, Liang Zhao, “Metal-ligand cooperative effect on intramolecular electron transfer in macrocycle-encircled copper-oxygen species”, CCS Chem. 2023, 5, 2171–2183.
7. Kui Xiao, Niyuan Zhang, Feifei Li, Dayong Hou, Xiaoyi Zhai, Wanhai Xu, Gelin Wang, Hao Wang, Liang Zhao, “Pro-oxidant response and accelerated ferroptosis caused by synergetic Au(I) release in hypercarbon-centered gold(I) cluster prodrugs”, Nat. Commun. 2022, 13, 4669.
8. Han Wu, Xin He, Biao Yang, Cui-Cui Li, Liang Zhao, “Assembly-Induced Strong Circularly Polarized Luminescence of Spirocyclic Chiral Silver(I) Clusters”, Angew. Chem. Int. Ed. 2021, 60, 1535.
9. Kui Xiao, Yu Zhao, Jun Zhu, Liang Zhao, “Hyperconjugative aromaticity and protodeauration reactivity of polyaurated indoliums”, Nat. Commun. 2019, 10, 5639.
10. Siqi Zhang, Liang Zhao, “Macrocycle-encircled polynuclear metal clusters: Controllable synthesis, reactivity studies, and applications”, Acc. Chem. Res. 2018, 51, 2535-2545.
