undefined



Dr. Shaoguang Zhang, Assistant Professor, PI

Department of Chemistry, Tsinghua University

Haidian, Beijing 100084, China

Email: sgzhang@tsinghua.edu.cn

ORCID ID: 0000-0002-0931-321X


Education

2004-2008        B.En. in Pharmaceutical Engineering, Beijing Institute of Technology (Advisors: Prof. Zhiming Zhou, Prof. Zhenfeng Xi)

2008-2013        Ph.D. in Organic Chemistry, Peking University (Advisors: Prof. Zhenfeng Xi, Prof. Wen-Xiong Zhang)


Professional Experience

2013-2016         Postdoctoral Researcher, Pacific Northwest National Lab, USA (Advisor: Dr. R. Morris Bullock)

2016-2018         Postdoctoral Researcher, University of Pennsylvania, USA (Advisor: Prof. Neil C. Tomson)

2018-2020         Senior Research Scientist, Process Research and Development, Merck & Co. Inc., USA

2020-present     Associate Professor, PI, Department of Chemistry, Tsinghua University


Fields of Interest

Organometallic chemistry, main-group element chemistry, organic synthesis


The research group is recruiting postdoctoral researchers and research assistants in the fields of organometallic chemistry, organic synthesis, and computational organic chemistry. Interested candidates are invited to contact us via email.



Honors and Awards

2025 Tsinghua University Teaching Achievement Award (1st Prize)

2024 Tsinghua University Annual Teaching Excellence Award

2024 Young Teachers' Teaching Competition (1st Prize)

2023 National Natural Science Award (2nd Prize, 4th Contributor)

2023 Outstanding Supervisor of Student Research Training (1st Prize)

2015 CIBA/YCC Young Scientist Travel Award, ACS Younger Chemists Committee

2015 Outstanding Performance Award, Pacific Northwest National Laboratory

2013 Reaxys PhD Prize (Finalist), Reed Elsevier Properties SA

2013 Excellent Doctoral Dissertation, Peking University

2012 National Scholarship for Graduate Student, Ministry of Education, China

2011 Principal’s Scholarship, Peking University



Publications

1. Li, Z.; Wang, Q.; Gao, R.; Zhang, S.* One- and Two-Electron Carbon–Halide Bond Activation at a Phosphorus Center. Angew. Chem. Int. Ed. 2025, doi: 10.1002/anie.202521209. (Hot Paper)

2. Su, Z.; Zhong, M.;* Meng, X.; Gao, R.; Li, J.;* Yuan, M.; Roesky, H. W.;* Zhang, S.* Bifunctional Silylene–Aminoborane Enables Cooperative Activation of Unsaturated Bonds and Access to Heteroatom‐Enriched Polycycle. Angew. Chem. Int. Ed. 2025, 64, e202515808.

3. Zhong, M.;*, Su, Z.; Jiang, X.; Chen, L.; Guo, Y.; Roesky, H. W.;* Zhang, S.* A Spatially Separated Germylene-Carbene Compound for Site-Selective Small Molecule Activation. Inorg. Chem. 2025, 64, 14428–14436.

4. Zhang, S.; Ruccolo, S.;* Fryszkowska, A.; Klapars, A.; Marshall, N. M.; Strotman, N. A. Electrochemical Activation of Galactose Oxidase: Mechanistic Studies and Synthetic Application. ACS Catal. 2021, 11, 7270–7280.

5. Zhang, S.; Cui, P.; Liu, T.; Wang, Q.; Longo, T. J.; Thierer, L. M.; Manor, B. C.; Gau, M. R.; Carroll, P. J.; Papaefthymiou, G. C.; Tomson, N. C.* “N–H Bond Formation at a Diiron Bridging Nitride.” Angew. Chem. Int. Ed. 2020, 59, 15215–15219.

6. Zhang, S.; Wang, Q.; Thierer, L. M.; Weberg, A. B.; Gau, M. R.; Carroll, P. J.; Tomson, N. C.* “Tuning Metal–Metal Interactions through Reversible Ligand Folding in a Series of Dinuclear Iron Complexes.” Inorg. Chem. 2019, 58, 12234-12244.

7. Zhang, S.; Appel, A. M.; Bullock, R. M.* “Reversible Heterolytic Cleavage of the H-H Bond by Molybdenum Complexes: Controlling the Dynamics of Exchange Between Proton and Hydride.”J. Am. Chem. Soc. 2017, 139, 7376–7387.

8. Zhang, S.; Zhang, W.-X.; Xi, Z.* “Semibullvalene and Diazasemibullvalene: Recent Advances in the Synthesis, Reaction Chemistry, and Synthetic Applications.”Acc. Chem. Res. 2015, 48, 1823–1831.

9. Zhang, S.; Zhang, W.-X.; Xi, Z.* “Lewis Acid-Catalyzed Site-Selective Cycloadditions of 2,6-Diazasemibullvalenes with Isocyanides, Azides and Diazo Compounds: Novel Reaction Patterns Leading to Diaza- and Triaza-Brexadiene Derivatives.” Angew. Chem. Int. Ed. 2013, 52, 3485-3489.

10. Zhang, S.; Wei, J.; Zhan, M.; Luo, Q.; Wang, C.; Zhang, W.-X.; Xi, Z.* “2,6-Diazasemibullvalenes: Synthesis, Structural Characterization, Theoretical Analysis and Reaction Chemistry. ” J. Am. Chem. Soc. 2012, 134, 11964–11967.

11. Zhang, S.; Zhang, W.-X.; Zhao, J.; Xi, Z.* “Cleavage and Reorganization of Zr−C/Si−C Bonds Leading to Zr/Si−N Organometallic and Heterocyclic Compounds.” J. Am. Chem. Soc. 2010, 132, 14042-14045.