Aijun TONG

Professor Aijun TONG 


Department of Chemistry, Tsinghua University, Beijing 100084, China

Office: Rm. D317 School of Sciences Building

Tel: 86-10-62787682



Prof. Aijun Tong got her B.S. (1983) in Chemistry from Xinjiang University, China, M.S. (1989) and Ph.D (1992) in Analytical Chemistry from Meisei University, Tokyo, Japan. She joined the Department of Chemistry, Tsinghua University as a Lecturer from 1992, and then promoted to Associate Professor (1996) and Professor (2003). Her current research directions include the development of novel fluorescence analytical methods for bioimaging, diagnosis and therapy of diseases, as well as their mechanisms in single cell level. Her work has resulted in over 100 peer-reviewed publications and book chapters.

Research Area:

Fluorescent probes, sensors, and functional materials for bioimaging and detection


Analytical Chemistry

Instrumental Analysis B

Advanced Analytical Chemistry (highly sensitive detection methods)

Selected Publications:

1.Xiaokun Zheng, Wenbo Wu, Yue Zheng, Yiwen Ding, Yu Xiang, Bin Liu*, Aijun Tong*, Organic Nanoparticles with Persistent Luminescence for In Vivo Afterglow Imaging-Guided Photodynamic Therapy, Chem. Eur. J., 2021, 27(23), 6911-6916. (Cover page,

2.Jingyi Wang, Jiachen Shang, Yu Xiang, Aijun Tong*, General Method for Post-Synthetic Modification of Oligonucleotides Based on Oxidative Amination of 4Thio-2′-deoxyuridine, Bioconjugate Chem., 2021, 32(4), 721-728. (Cover page,

3.Yue Zheng, Yiwen Ding, Jiajun Ren, Yu Xiang, Zhigang Shuai*, Aijun Tong*, Simultaneously and Selectively Imaging a Cytoplasm Membrane and Mitochondria Using a Dual-Colored Aggregation-Induced Emission Probe, Anal. Chem., 2020, 92(21), 14494-14500. (Cover page,

4.Lu Peng, Ruirui Wei, Yifei Guo, Xiaokun Zheng, Yue Zheng, Yiwen Ding, Yu Xiang, Aijun Tong*, Tuning Emission Wavelength of Polymorphous Crystal via Controllable Alky Chain Stacking and Its Vapor- and Thermo- Responsive Fluorescence, Chem. Eur. J., 2019, 25(34), 8043-8052.(Cover page,

5.Lu Peng, Shidang Xu, Xiaokun Zheng, Xiamin Cheng, Ruoyu Zhang, Jie Liu, Bin Liu*, Aijun Tong*, Rational Design of a Red-Emissive Fluorophore with AIE and ESIPT Characteristics and Its Application in Light-up Sensing of Esterase, Anal. Chem., 2017, 89(5), 3162-3168.

6.Xiaokun Zheng, Yue Zheng, Lu Peng, Yu Xiang, Aijun Tong*, Mechanoresponsive fluorescence of 2-aminobenzophenone derivatives based on amorphous phase to crystalline transformation with high “off-on” contrast ratio, J. Phys. Chem. C, 2017, 121(39), 21610-21615.

7.Yue Zheng, Xiaokun Zheng, Lu Peng, Yu Xiang, Aijun Tong*, Photoactivatable Aggregation-Induced Emission of Triphenylmethanol, Chem. Comm., 2017, 53(81), 11130-11133.

8.Kai Li, Yu Xiang, Xiaoyan Wang, Ji Li, Rongrong Hu, Aijun Tong*, Ben Zhong Tang*, Reversible Photochromic System Based on Rhodamine B Salicylaldehyde Hydrazone Metal Complex, J. Am. Chem. Soc., 2014, 136(4), 1643-1649.

9.Yu Xiang, Aijun Tong*, Yi Lu*, Abasic site-containing DNAzyme and aptamer for label-free fluorescent detection of Pb2+ and adenosine with high sensitivity, selectivity, and tunable dynamic range, J. Am. Chem. Soc., 2009, 131(42), 15352-15357.

10.Weixin Tang, Yu Xiang*, Aijun Tong*, Salicylaldehyde azines as fluorophores of induced emission enhancement characteristics, J. Org. Chem., 2009, 74(5), 2163-2166.